II型脊髓性肌萎缩症患者中枢运动传导的保留情况
Preservation of central motor conduction in patients with spinal muscular atrophy type II.
作者信息
Imai T, Matsuya M, Matsumoto H, Ishikawa Y, Minami R
机构信息
Department of Neurology, School of Medicine, Sapporo Medical University, Japan.
出版信息
Brain Dev. 1995 Nov-Dec;17(6):432-5. doi: 10.1016/0387-7604(95)00087-9.
We evaluated the central (motor cortex to C8 motoneuron) and peripheral (C8 motoneuron to the muscle) motor conduction in 14 limbs of 7 patients with the intermediate form of spinal muscular atrophy (SMA II). The central motor conduction time (CMCT) was calculated using motor evoked potentials (MEPs) by transcranial magnetic stimulation and the results of a conventional F wave study. Peripheral conduction abnormality was found in 6 median nerves (43%) and 10 ulnar nerves (71%). Even in these patients with peripheral conduction abnormalities, the CMCT was consistently normal whenever the MEP was recorded. These results indicate that the motor conduction of the corticospinal fibers remains normal in SMA II.
我们评估了7例中间型脊髓性肌萎缩症（SMA II）患者14条肢体的中枢（运动皮层至C8运动神经元）和外周（C8运动神经元至肌肉）运动传导情况。通过经颅磁刺激利用运动诱发电位（MEP）以及传统F波研究结果计算中枢运动传导时间（CMCT）。在6条正中神经（43%）和10条尺神经（71%）中发现外周传导异常。即使在这些存在外周传导异常的患者中，只要记录到MEP，CMCT始终正常。这些结果表明，SMA II患者皮质脊髓纤维的运动传导保持正常。
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