Davis C L, Gretch D R, Carithers R L
University of Washington Medical Center, Seattle, USA.
Infect Dis Clin North Am. 1995 Dec;9(4):925-41.
Hepatitis B infection can add significantly to the morbidity and mortality of transplantation. Patients with hepatitis B can have severe recurrent disease following liver transplantation. Reactivation of occult disease can occur during chemotherapy or immunosuppression. Hepatitis B also can be acquired at the time of transplantation. Intensive study of transplant patients with hepatitis B has led to a new understanding of the immunobiology of hepatitis B virus.
乙肝感染会显著增加移植的发病率和死亡率。乙肝患者在肝移植后可能会出现严重的复发疾病。隐匿性疾病在化疗或免疫抑制期间可能会重新激活。乙肝也可能在移植时获得。对乙肝移植患者的深入研究使人们对乙肝病毒的免疫生物学有了新的认识。
