Clements B, Lewis H, Lewis H, McKinstrey S, Gray J, Byrnes D
Department of Surgery, Institute of Clinical Science, Belfast, Ireland.
Ann Plast Surg. 1995 Dec;35(6):650-3. doi: 10.1097/00000637-199512000-00016.
Marjolin's ulcer is an uncommon condition in which malignant transformation occurs in a chronic inflammatory focus. It was originally described in association with a thermal injury, however, its occurrence with protean chronic inflammatory foci has been described. We report the occurrence of and aggressive squamous carcinoma 3 decades after a high voltage electric mark injury to the scalp. This is the first such case described in the literature. The case supportively highlights the role of chronic inflammation and sepsis in epidermal scar cancer development, and it underlines the importance of appropriate wound management initially and expeditious treatment of sepsis and resistant skin ulceration because the malignant behavior of these tumors is aggressive and unpredictable.
马乔林溃疡是一种罕见病症，即在慢性炎症病灶中发生恶性转化。它最初是与热损伤相关联被描述的，然而，其在多种慢性炎症病灶中的发生情况也有报道。我们报告了一例头皮高压电标记伤30年后发生侵袭性鳞状细胞癌的病例。这是文献中首例此类病例的描述。该病例有力地凸显了慢性炎症和脓毒症在表皮瘢痕癌发生中的作用，并强调了最初进行恰当伤口处理以及迅速治疗脓毒症和顽固性皮肤溃疡的重要性，因为这些肿瘤的恶性行为具有侵袭性且不可预测。
