Curry S S, Gaither D H, King L E
J Am Acad Dermatol. 1981 Jun;4(6):673-8. doi: 10.1016/s0190-9622(81)70068-9.
Squamous cell carcinomas have been reported to arise within acne conglobata and hidradenitis suppurativa. A case report of a secondary squamous cell carcinoma (SSCC) arising in the third member of the follicular occlusion triad, dissecting perifolliculitis of the scalp (Hoffman's disease, perifolliculitis capitis abscedens et suffodiens) is presented. The fatal outcome of this case and a review of the literature emphasize the biologic aggressiveness of SSCCs arising in chronic inflammatory lesions or scars (Marjolin's ulcers). Compared to squamous cell carcinomas arising in actinic keratoses, the metastasis rate of these carcinomas arising in chronic inflammatory lesions is so high that early and aggressive therapy appear indicated.
据报道，鳞状细胞癌可发生于聚合性痤疮和化脓性汗腺炎内。本文报告了一例继发于毛囊闭锁三联征的第三个成员——头皮穿掘性毛囊周围炎（霍夫曼病，头皮穿掘性毛囊周围炎）的鳞状细胞癌（SSCC）病例。该病例的致命结局以及文献回顾强调了发生于慢性炎性病变或瘢痕（Marjolin溃疡）中的SSCC的生物学侵袭性。与光化性角化病中发生的鳞状细胞癌相比，这些发生于慢性炎性病变中的癌转移率如此之高，以至于似乎需要早期积极治疗。
