Lozano A M, Hutchison W D, Dostrovsky J O
Department of Surgery, Toronto Hospital Neurological Centre, Canada.
Acta Neurochir Suppl. 1995;64:30-4. doi: 10.1007/978-3-7091-9419-5_7.
We describe microelectrode recording and stimulation techniques to delineate the cellular boundaries and neural projections of stereotactic brain targets. These techniques have applications in the surgery for pain, movement disorders and in psychosurgery. Neuronal records from stereotactic operations including thalamotomy, pallidotomy, cingulotomy and anterior capsulotomy are discussed. These tools are used to distinguish gray matter from white matter, to obtain direct measures of cellular activity in the target, to identify the physiological properties and receptive fields of the subpopulation of neurons at the electrode tip and to avoid lesion making induced injury to adjacent structures. Microelectrode recording and stimulation techniques improve physiological localization and decrease the possibility of unwanted neurological complications with functional stereotactic procedures.
我们描述了微电极记录和刺激技术，以描绘立体定向脑靶点的细胞边界和神经投射。这些技术在疼痛手术、运动障碍手术和精神外科手术中都有应用。文中讨论了立体定向手术（包括丘脑切开术、苍白球切开术、扣带回切开术和前囊切开术）中的神经元记录。这些工具用于区分灰质和白质，直接测量靶点中的细胞活动，识别电极尖端神经元亚群的生理特性和感受野，并避免损伤制造过程中对相邻结构的损伤。微电极记录和刺激技术改善了生理定位，并降低了功能性立体定向手术中出现不必要神经并发症的可能性。
