多巴胺能激动剂治疗帕金森病：综述
Dopaminergic agonists in the treatment of Parkinson's disease: a review.
作者信息
Piccoli F, Riuggeri R M
机构信息
Institute of Neuropsychiatry, University of Palermo, Italy.
出版信息
J Neural Transm Suppl. 1995;45:187-95.
Dopaminergic agonists represent an important class of drugs in Parkinson's Disease, useful: a) in delaying the beginning of L-dopa therapy; b) in supporting it, reducing its dosage and widen the therapeutic window; c) moreover, as the disease advances, in trying to treat motor fluctuations. Authors describe briefly the problems caused by long term L-dopa therapy, and analyze, separately, the characteristics of the most important dopaminergic agonists currently utilized in the treatment of PD.
多巴胺能激动剂是帕金森病治疗中的一类重要药物，其作用如下：a）延迟左旋多巴治疗的起始时间；b）辅助左旋多巴治疗，减少其用量并拓宽治疗窗口；c）此外，随着疾病进展，用于治疗运动波动。作者简要描述了长期左旋多巴治疗所引起的问题，并分别分析了目前用于治疗帕金森病的最重要的多巴胺能激动剂的特点。
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