Shojaku H, Watanabe Y, Mizukoshi K, Kitahara M, Yazawa Y, Watanabe I, Ohkubo J
Department of Otolaryngology, Toyama Medical and Pharamaceutical University, Japan.
Acta Otolaryngol Suppl. 1995;520 Pt 2:415-8. doi: 10.3109/00016489509125286.
In order to clarify the characteristics of severe cases of Meniére's disease (MD), we analyzed various epidemiological factors such as sex ratio, past history, complication, cause of onset of vertiginous attacks, etc., in a series of 958 patients with definite MD. Data were obtained from the three Japan-wide surveys of MD conducted by the Meniére's Disease Research Committee of Japan (1975-76) and the Vestibular Disorders Research Committee of Japan (1982-84 & 1990). Following the ideas proposed by the members of the Vestibular Disorder Research Committee of Japan, we divided severe cases into three categories according to the following criteria i) bilateral MD cases (BMD), ii) unilateral MD cases with prolonged disabled vertigo (UPDV), iii) unilateral MD cases with profound hearing loss (UPHL). About 40% of the subjects were classified as severe cases (UPDV: 23%; BMD: 9%; UPHL: 6%). The ratio of otitis media in past history was statistically different between severe cases and non-severe patients (p < 0.05), suggesting that otitis media in the past may contribute to the severity of Meniére's disease.
为明确梅尼埃病（MD）重症病例的特征，我们分析了958例确诊MD患者的各种流行病学因素，如性别比例、既往史、并发症、眩晕发作的病因等。数据来自日本梅尼埃病研究委员会（1975 - 76年）以及日本前庭疾病研究委员会（1982 - 84年和1990年）在日本全国范围内开展的三项MD调查。按照日本前庭疾病研究委员会成员提出的思路，我们根据以下标准将重症病例分为三类：i）双侧MD病例（BMD），ii）单侧MD伴持续性致残性眩晕病例（UPDV），iii）单侧MD伴重度听力损失病例（UPHL）。约40%的受试者被归类为重症病例（UPDV：23%；BMD：9%；UPHL：6%）。重症病例与非重症患者过去中耳炎的比例在统计学上存在差异（p < 0.05），这表明过去的中耳炎可能与梅尼埃病的严重程度有关。
