Mizukoshi K, Watanabe Y, Shojaku H, Ito M, Ishikawa M, Aso S, Asai M, Motoshima H
Department of Otolaryngology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Japan.
Acta Otolaryngol Suppl. 1995;520 Pt 2:412-4. doi: 10.3109/00016489509125285.
In order to clarify the influence of a cold front (CF) upon the onset of Meniére's disease (MD), major CFs were defined by meteorological observations, and the influence of CFs on MD was evaluated by using the time n method. From our preliminary study it was seen that the onset of MD had its highest incidence exactly on days where a CF passed by. Out of the patients with MD, sudden deafness (SD) and Bell's palsy (BP) who visited our neurotological clinic of the Toyama Medical and Pharmaceutical University from 1987 to 1992, 67 MD patients, 70 SD patients and 70 BP patients could clearly define the date of the onset of their disease, and were therefore selected for this epidemiological study. Thirty-six our of the 67 MD patients had the first attack on the day when a CF passed by or on the next day. The results obtained from these studies were as follows. i) The onset of MD was influenced by the passing of a CF, and this influence was more specific in MD than in SD or BP. ii) In the 36 CF influence MD patients, the majority were over the forty years, and their hearing level was worse than that of the other 31 MD patients during the observation periods.
为了阐明冷锋（CF）对梅尼埃病（MD）发病的影响，通过气象观测定义主要冷锋，并采用时间n法评估冷锋对梅尼埃病的影响。从我们的初步研究中可以看出，梅尼埃病的发病在冷锋经过的当天发病率最高。在1987年至1992年期间到富山医科药科大学神经耳科门诊就诊的梅尼埃病患者、突发性聋（SD）患者和贝尔麻痹（BP）患者中，67例梅尼埃病患者、70例突发性聋患者和70例贝尔麻痹患者能够明确界定其疾病的发病日期，因此被选入本流行病学研究。67例梅尼埃病患者中有36例在冷锋经过当天或次日首次发作。这些研究得到的结果如下。i） 梅尼埃病的发病受冷锋经过的影响，且这种影响在梅尼埃病中比在突发性聋或贝尔麻痹中更具特异性。ii） 在36例受冷锋影响的梅尼埃病患者中，大多数年龄超过40岁，且在观察期间他们的听力水平比其他31例梅尼埃病患者更差。
