Fonn D, Gauthier C A, Pritchard N
Centre for Contact Lens Research, School of Optometry, University of Waterloo, Ontario, Canada.
Optom Vis Sci. 1995 Dec;72(12):857-63. doi: 10.1097/00006324-199512000-00003.
Patient preferences and ocular responses were compared between rigid and soft contact lenses by randomly fitting 32 neophyte subjects with a rigid lens in 1 eye and a soft lens in the contralateral eye. Twenty-seven of 32 subjects completed the 3-month study and 16 subjects were willing to continue for an additional 3-month extension. Subjects preferred the comfort and handling of the soft lens but preferred the vision provided by the rigid lens and initially its ease of maintenance. There was also a marked preference for the soft lens when all aspects of lens wear were compared. Objectively, the rigid lenses were responsible for more ocular changes than the soft lenses. Palpebral aperture sizes of the rigid gas permeable (RGP) wearing eyes decreased significantly (0.5 mm; p < 0.05) compared to the soft lens wearing eyes. The incidence of corneal staining was significantly greater in the rigid lens wearing eye (50% RGP vs. 22% soft) but limbal injection was greater in the soft lens wearing eye (18% soft vs. 6% RGP). Refractive sphere, cylinder, and corneal astigmatism decreased in the rigid lens wearing eye after 3 months. This daily wear clinical trial has shown a marked subjective preference for wearing soft lenses with fewer short-term ocular effects.
通过随机为32名新手受试者的一只眼睛佩戴硬性隐形眼镜，另一只眼睛佩戴软性隐形眼镜，比较了硬性和软性隐形眼镜的患者偏好及眼部反应。32名受试者中有27名完成了为期3个月的研究，16名受试者愿意继续进行额外3个月的延长研究。受试者更喜欢软性隐形眼镜的舒适度和佩戴便利性，但更喜欢硬性隐形眼镜提供的视力以及最初它的易于保养性。当比较隐形眼镜佩戴的各个方面时，对软性隐形眼镜也有明显的偏好。客观上，硬性隐形眼镜比软性隐形眼镜引起更多的眼部变化。与佩戴软性隐形眼镜的眼睛相比，佩戴硬性透气性（RGP）隐形眼镜的眼睛睑裂大小显著减小（0.5毫米；p<0.05）。佩戴硬性隐形眼镜的眼睛角膜染色发生率显著更高（RGP为50%，软性为22%），但佩戴软性隐形眼镜的眼睛角膜缘充血更严重（软性为18%，RGP为6%）。3个月后，佩戴硬性隐形眼镜的眼睛的屈光球镜、柱镜和角膜散光度数下降。这项日戴型临床试验表明，在短期眼部影响较少的情况下，佩戴软性隐形眼镜有明显的主观偏好。
