两名同时感染人类免疫缺陷病毒和I型人类嗜淋巴细胞病毒的患者出现免疫缺陷及CD4 T淋巴细胞计数升高
Immunodeficiency and elevated CD4 T lymphocyte counts in two patients coinfected with human immunodeficiency virus and human lymphotropic virus type I.
作者信息
Fantry L, De Jonge E, Auwaerter P G, Lederman H M
机构信息
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287-3923, USA.
出版信息
Clin Infect Dis. 1995 Dec;21(6):1466-8. doi: 10.1093/clinids/21.6.1466.
We describe two patients who were coinfected with human immunodeficiency virus (HIV) and human T-cell lymphotropic virus (HTLV) type I. They had clinical evidence of immunodeficiency (anergy, oral candidiasis, and disseminated herpes zoster) despite having elevated CD4 T lymphocyte counts (range, 2,450-5,292/mm3). We conclude that CD4 lymphocyte counts may not be reliable markers of immunologic competence in patients coinfected with HIV and HTLV-I.
我们描述了两名同时感染人类免疫缺陷病毒（HIV）和I型人类T细胞嗜淋巴细胞病毒（HTLV）的患者。尽管他们的CD4 T淋巴细胞计数升高（范围为2450 - 5292/mm³），但仍有免疫缺陷的临床证据（无反应性、口腔念珠菌病和播散性带状疱疹）。我们得出结论，在同时感染HIV和HTLV-I的患者中，CD4淋巴细胞计数可能不是免疫能力的可靠标志物。
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