Kauppinen M, Saikku P
Department of Oulu, National Public Health Institute, Finland.
Clin Infect Dis. 1995 Dec;21 Suppl 3:S244-52. doi: 10.1093/clind/21.supplement_3.s244.
The association of Chlamydia pneumoniae with pneumonia was first reported in 1985. This review summarizes the data collected during the subsequent 10 years on the prevalence, clinical features, diagnosis, and treatment of this disease, which is now associated with approximately 10% of all cases of pneumonia worldwide. Primary infections are documented most often in schoolchildren and young adults, while reinfections are prominent among the elderly. C. pneumoniae pneumonia is difficult to diagnose; its onset is often insidious, with nonpurulent sputum and without leukocytosis. The microbiological diagnosis is based on the results of serological tests, polymerase chain reaction, and culture. Tetracyclines and macrolides are effective in the treatment of C. pneumoniae pneumonia, as are new quinolones.
肺炎衣原体与肺炎的关联最早于1985年被报道。本综述总结了随后10年收集的关于该疾病的患病率、临床特征、诊断和治疗的数据，目前全球约10%的肺炎病例与之相关。原发性感染最常见于学龄儿童和年轻人，而再次感染在老年人中较为突出。肺炎衣原体肺炎难以诊断；其起病往往隐匿，有非脓性痰液且无白细胞增多。微生物学诊断基于血清学检测、聚合酶链反应和培养结果。四环素类和大环内酯类药物对肺炎衣原体肺炎有效，新型喹诺酮类药物也有效。
