Nagel T R, Schunk J E
Department of Pediatrics, University of Utah, Salt Lake City, USA.
Pediatr Emerg Care. 1995 Dec;11(6):369-71. doi: 10.1097/00006565-199512000-00009.
Felbamate was approved in July 1993 for use alone or in combination with other antiepileptic drugs for partial seizures and Lennox-Gastaut syndrome. We report an overdose of felbamate in a teenage female patient who, in a suicide gesture, ingested eight times her maximum dose and suffered only mild side effects. This first report of a felbamate overdose is presented and followed by a discussion of felbamate's effectiveness, pharmacology, adverse effects, and drug interactions.
非氨酯于1993年7月被批准单独使用或与其他抗癫痫药物联合用于治疗部分性癫痫发作和伦诺克斯-加斯东综合征。我们报告了一名青少年女性患者过量服用非氨酯的情况，该患者出于自杀意图，服用了八倍于其最大剂量的药物，但仅出现了轻微的副作用。本文首次报道了非氨酯过量服用的案例，并随后讨论了非氨酯的疗效、药理学、不良反应及药物相互作用。
