Parikh F R, Kamat S A, Kodwaney G G, Balaiah D
Department of Infertility Management and Assisted Reproduction, Jaslok Hospital and Research Centre, Bombay, India.
Fertil Steril. 1996 Sep;66(3):440-5. doi: 10.1016/s0015-0282(16)58516-1.
To assess sperm characteristics and fertility before and after varicocelectomy using computer-assisted semen analysis (CASA).
Preoperative and postoperative sperm parameters of infertile men with varicocele were analyzed statistically and the outcome of pregnancy was determined.
Department of Infertility Management and Assisted Reproduction, Jaslok Hospital and Research Centre, Bombay.
Semen samples of 49 men with varicocele-related infertility were analyzed using CASA.
Sperm parameters of 26 men who underwent varicocelectomy were evaluated 3, 6, and 9 months postoperatively. Conception, occurring either naturally or therapeutically, was recorded.
Evaluation of improvement of sperm parameters after surgery.
Sperm count, motility parameters, curvilinear velocity, straightline velocity, lateral head displacement, and normal morphology were significantly lower in men with varicocele. Postoperatively, there was significant improvement in count, motility, and normal morphology, with a decrease in proportion of acrosome-deficient heads and tapering forms. After varicocelectomy, 46.2% of the men had normal semen parameters, with the overall pregnancy rate being 50%.
Computer-assisted semen analysis provides the potential for accurate quantitative evaluation of semen in men with varicocele. Varicocelectomy results in improvement in semen quality with pregnancy rates of 50%.
使用计算机辅助精液分析（CASA）评估精索静脉曲张切除术前后的精子特征和生育能力。
对精索静脉曲张不育男性的术前和术后精子参数进行统计学分析，并确定妊娠结局。
孟买贾斯洛医院及研究中心不孕不育管理与辅助生殖科。
对49例精索静脉曲张相关性不育男性的精液样本进行CASA分析。
对26例行精索静脉曲张切除术的男性，在术后3、6和9个月评估其精子参数。记录自然受孕或治疗后受孕情况。
评估术后精子参数的改善情况。
精索静脉曲张男性的精子计数、活力参数、曲线速度、直线速度、头部横向位移和正常形态显著降低。术后，精子计数、活力和正常形态有显著改善，顶体缺陷头部和逐渐变细形态的比例降低。精索静脉曲张切除术后，46.2%的男性精液参数正常，总体妊娠率为50%。
计算机辅助精液分析为准确量化评估精索静脉曲张男性的精液提供了可能。精索静脉曲张切除术可改善精液质量，妊娠率为50%。
