Nemoto T, Nagasawa T, Aoki S, Suzuki K, Shimizu Y
Public Nanokaichi Hospital, Gunma, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1995 Dec;33 Suppl:91-6.
Classification of bronchial asthma with Rackemann's system or Swineford's system is too simple to be clinically useful. We developed a new system for classifying patients with asthma. Patients were assigned a "0" or a "1" for each of five criteria: the presence or absence of (1) steroid dependence, (2) allergy, and (3) sensitivity to aspirin, and whether or not their asthma was judged to be (4) hereditary and (5) infectious. For example, patients who were sensitive to aspirin and whose asthma was judged to be of the infectious type were classified as 00101. A total of 434 patients with asthma were studied (185 males and 249 females, ranging in age from 10 to 93 years). The patients were classified into 32 subtypes (shown in an accompanying table), and the data were compared to the results of classification by other methods. The present system may be more useful than those of Rackeman or Swineford, because it takes heredity and sensitivity to aspirin into account. A total of 103 patients could not be classified by Swineford's system: those in classes 00000, 00010, 00100, 00110, 10000, 10010, 10100, and 10110. We expect this new system for classifying bronchial asthma to be clinically useful.
采用拉克曼系统或斯温福德系统对支气管哮喘进行分类过于简单,在临床上并无实用价值。我们开发了一种新的哮喘患者分类系统。根据五个标准为患者分别赋值“0”或“1”:(1)是否依赖类固醇、(2)是否过敏、(3)是否对阿司匹林敏感,以及其哮喘是否被判定为(4)遗传性的和(5)感染性的。例如,对阿司匹林敏感且哮喘被判定为感染型的患者被分类为00101。共研究了434例哮喘患者(185例男性和249例女性,年龄在10至93岁之间)。患者被分为32个亚型(见附表),并将数据与其他分类方法的结果进行比较。本系统可能比斯温福德或拉克曼系统更有用,因为它考虑了遗传因素和对阿司匹林的敏感性。共有103例患者无法用斯温福德系统分类:即00000、00010、00100、00110、10000、10010、10100和10110类的患者。我们期望这种新的支气管哮喘分类系统在临床上具有实用价值。