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基于免疫机制的支气管哮喘分类

[Classification of bronchial asthma based on immunological mechanisms].

作者信息

Morita Y

机构信息

Department of Internal Medicine and Physical Therapy Faculty of Medicine, University of Tokyo.

出版信息

Nihon Kyobu Shikkan Gakkai Zasshi. 1995 Dec;33 Suppl:100-3.

PMID:8752491
Abstract

A classification of bronchial asthma based on immunological mechanisms is proposed. For this classification, asthma was divided into antigen-dependent and antigen-independent types. Antigen-dependent asthma was classified into antibody-dependent and antibody-independent sub-types. Antibody-dependent asthma was further subdivided into IgE-mediated, IgG-mediated, immune complex-mediated, and complement-mediated sub-types. Diisocyanate asthma was considered to be an example of antibody-independent asthma. Exercise-induced asthma and drug-induced asthma, such as aspirin-induced asthma, were included in the sub-type of antigen-independent asthma.

摘要

提出了一种基于免疫机制的支气管哮喘分类方法。基于此分类,哮喘被分为抗原依赖性和抗原非依赖性类型。抗原依赖性哮喘又分为抗体依赖性和抗体非依赖性亚型。抗体依赖性哮喘进一步细分为IgE介导型、IgG介导型、免疫复合物介导型和补体介导型。二异氰酸酯哮喘被认为是抗体非依赖性哮喘的一个例子。运动性哮喘和药物性哮喘,如阿司匹林诱发的哮喘,被纳入抗原非依赖性哮喘亚型。

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