Sobotka S, Ringo J L
Department of Physiology, University of Rochester Medical Center, New York 14642-8642, USA.
J Neurosci. 1996 Jul 1;16(13):4222-30. doi: 10.1523/JNEUROSCI.16-13-04222.1996.
Three macaques were trained on a task in which a sequence of single visual images was presented serially, and the monkeys signaled whether the image was a new or a repeated one. The optic chiasm and splenium of the corpus callosum were transected, leaving the anterior commissure as the only path for cortical interhemispheric transfer. Images were presented to only one eye at a time. Re-presentations of images to the same eye were recognized correctly in >95% of trials. A robust stimulus-specific adaptation (i.e., a reduced response to a repeated image) was seen in the population of single units recorded from inferotemporal cortex during these same trials. When an interhemispheric transfer was demanded of the animals (i.e., the re-presentation was made to the other eye), recognition performance was somewhat reduced, to 86% correct. Interestingly, in this situation the stimulus-specific adaptation disappeared completely. The disappearance occurred regardless of whether the transfer direction was from the hemisphere ipsilateral to the recording site to the hemisphere contralateral to the recording site, or vice versa. Thus, stimulus-specific adaptation in inferotemporal cortex units is not required for recognition.
对三只猕猴进行一项任务训练，在该任务中一系列单个视觉图像依次呈现，猴子需示意图像是新的还是重复的。切断视交叉和胼胝体压部，使前连合成为皮质半球间传递的唯一通路。每次仅向一只眼睛呈现图像。在超过95%的试验中，同一眼睛再次呈现的图像能被正确识别。在这些相同试验期间，从颞下皮质记录的单个神经元群体中观察到强烈的刺激特异性适应（即对重复图像的反应降低）。当要求动物进行半球间传递时（即向另一只眼睛再次呈现图像），识别性能有所下降，正确率降至86%。有趣的是，在这种情况下，刺激特异性适应完全消失。无论传递方向是从记录部位同侧的半球到记录部位对侧的半球，还是相反方向，这种消失都会发生。因此，颞下皮质神经元中的刺激特异性适应对于识别并非必需。
