Sanz L, Cervantes F, Mercader J M, Rozman M, Rozman C, Montserrat E
Escuela de Hematología Farreras-Valentí, Servicio de-Hematología, Hospital Cliníc i Provincial, Universidad de Barcelona.
Med Clin (Barc). 1996 Jun 22;107(4):143-5.
Although bone marrow biopsy is considered the best procedure to detect bone marrow involvement by Hodgkin's disease (HD), in recent years several studies have emphasized the value of magnetic resonance imaging (MRI). We present the case of a patient with HD apparently localized in a laterocervical lymph node, who also referred disestasiae at a region corresponding to D10 metamera. Bone marrow biopsy, vertebral TC and 67-Ga scintigraphy were all normal. However, a node of 1 cm in diameter was detected by MRI in the tenth dorsal vertebra. Because of the topographic coincidence between the patient's symptomatology and the MRI findings, the HD was considered to be in advanced stage and CMOPP/ABV chemotherapy was administered, this resulting in a rapid improvement of symptoms and disappearance of the MRI abnormalities. Since in the present case, the MRI determined a change in disease stage and treatment, the role of MRI as a complementary exploration of bone marrow biopsy to detect marrow involvement by HD is reviewed.
尽管骨髓活检被认为是检测霍奇金病（HD）骨髓受累的最佳方法，但近年来多项研究强调了磁共振成像（MRI）的价值。我们报告一例HD患者，其病变明显局限于颈外侧淋巴结，同时在对应于第10节段的区域也有感觉障碍。骨髓活检、脊椎计算机断层扫描（TC）和67镓闪烁扫描均正常。然而，MRI在第10胸椎发现一个直径1厘米的结节。由于患者症状与MRI表现的部位相符，HD被认为处于晚期，并给予CMOPP/ABV化疗，结果症状迅速改善，MRI异常消失。鉴于本例中MRI改变了疾病分期和治疗方案，本文对MRI作为骨髓活检的补充检查手段以检测HD骨髓受累的作用进行了综述。
