L'vova S P, Abaeva E M
Ontogenez. 1996 May-Jun;27(3):204-7.
We studied the total antioxidant activity, as well as the activity of the water-soluble portion of the antioxidant system and the activity of catalase and superoxide dismutase in the brain, liver, heart muscle, skeletal muscle, kidneys and blood serum of 1, 4, 6, 30, and 90-120-day-old rats. High antioxidant activity was detected in the tissues of the newborn animals. In the majority of the tissues, the total antioxidant activity and catalase activity peaked at days 14-30 of development. Some tissue specificity of age-related changes has been found for individual components of the antioxidant system.
我们研究了1日龄、4日龄、6日龄、30日龄以及90 - 120日龄大鼠的大脑、肝脏、心肌、骨骼肌、肾脏和血清中的总抗氧化活性、抗氧化系统水溶性部分的活性以及过氧化氢酶和超氧化物歧化酶的活性。在新生动物的组织中检测到高抗氧化活性。在大多数组织中,总抗氧化活性和过氧化氢酶活性在发育的第14 - 30天达到峰值。已发现抗氧化系统的各个组分存在一些与年龄相关变化的组织特异性。