Budowle B, Woller J, Koons B W, Furedi S, Errera J D, Padar Z
Forensic Science Research and Training Center, FBI Academy, Quantico, VA, USA.
J Forensic Sci. 1996 Jul;41(4):667-70.
Hungarian population data for the loci LDLR, GYPA, HBGG, D7S8, Gc, HLA-DQA1, and D1S80 were generated. The genotype frequency distributions for the loci do not deviate from Hardy Weinberg expectations. Furthermore, there was little evidence for departures from expectations of independence between the loci. Using a test for homogeneity all the loci were similar between two Hungarian population samples and only the HLA-DQA1 locus was statistically different between Hungarians and US Caucasians. There generally would be little forensic differences, whether a Hungarian or a US Caucasian database was used, for estimating multiple locus profile frequencies for the seven PCR-based loci.
生成了匈牙利人群中低密度脂蛋白受体(LDLR)、血型糖蛋白A(GYPA)、β-球蛋白(HBGG)、D7S8、维生素D结合蛋白(Gc)、人白细胞抗原-DQA1(HLA-DQA1)和D1S80基因座的数据。这些基因座的基因型频率分布符合哈迪-温伯格平衡预期。此外,几乎没有证据表明这些基因座之间存在偏离独立性预期的情况。通过同质性检验发现,两个匈牙利人群样本之间所有基因座都相似,只有HLA-DQA1基因座在匈牙利人和美国白种人之间存在统计学差异。对于基于七个聚合酶链反应(PCR)的基因座估计多位点谱频率,无论使用匈牙利数据库还是美国白种人数据库,通常在法医鉴定方面差异不大。