Zapata Morán A L, Santamaría Ríos M M, Alvarez Irías M, Salazar Vanegas S, Müller U
Universidad Nacional Autónoma de Nicaragua.
Bol Oficina Sanit Panam. 1996 Jun;120(6):483-90.
This work reports on a preliminary study carried out in Nicaragua to build a profile of the contamination of cow's milk with 10 organochlorine pesticides and make recommendations based on the findings. Between December 1993 and March 1994, milk samples were collected from 48 different sites in the country. The samples were analyzed for residues of hexachlorobenzene (HCB), alpha-BHC, lindane, aldrin, dieldrin, oxychlordane, heptachlor epoxide, and the principal metabolites of DDT (p,p'-TDE, p,p'-DDE, and p,p'-DDT) by means of solid-phase extraction from milk fat, and the quantity of the residues was determined by gas chromatography with electron capture detection. Heptachlor epoxide was found in 1 milk sample, dieldrin in 1, lindane in 3, oxychlordane in 3, alpha-BHC in 3, aldrin in 6, HCB in 9, and metabolites of DDT in 39 (81% of the samples). The six samples most heavily contaminated with by-products of DDT came from the departments of León and Chinandega, in the Pacific region, where there used to be intensive cotton production. The highest concentration was found in the sample from Malpaisillo, with 1105 micrograms of pesticide per kg of milk fat. The authors recommend that studies should be done so that the risk of contamination of other food products can be estimated, and that the public's health should be protected through strict control of the production or importation, storage, sale, and use of organochlorine pesticides.
这项工作报告了在尼加拉瓜进行的一项初步研究,旨在建立牛奶中10种有机氯农药的污染情况档案,并根据研究结果提出建议。1993年12月至1994年3月期间,从该国48个不同地点采集了牛奶样本。通过从乳脂中进行固相萃取,分析样本中六氯苯(HCB)、α-六六六、林丹、艾氏剂、狄氏剂、氧氯丹、七氯环氧化物以及滴滴涕的主要代谢物(p,p'-三氯杀螨醇、p,p'-滴滴伊和p,p'-滴滴涕)的残留量,并通过带有电子捕获检测的气相色谱法测定残留量。在1个牛奶样本中发现了七氯环氧化物,1个样本中发现了狄氏剂,3个样本中发现了林丹,3个样本中发现了氧氯丹,3个样本中发现了α-六六六,6个样本中发现了艾氏剂,9个样本中发现了六氯苯,39个样本(占样本总数的81%)中发现了滴滴涕的代谢物。滴滴涕副产物污染最严重的6个样本来自太平洋地区的莱昂省和奇南德加省,那里曾经有过密集的棉花生产。在马尔帕西洛采集的样本中发现的浓度最高,每千克乳脂中含有1105微克农药。作者建议应开展研究,以便能够估计其他食品的污染风险,并通过严格控制有机氯农药的生产或进口、储存、销售和使用来保护公众健康。