Chikuni O, Skare J U, Nyazema N, Polder A
University of Zimbabwe Medical School, Department of Clinical Pharmacology, Avondale, Harare.
Cent Afr J Med. 1991 May;37(5):136-41.
Residue levels of the chlorinated hydrocarbons p,p -DDT, p,p, -DDE, p,p TDE, p,p -DDT, alpha-beta-gamma-hexachlorocyclohexane (HCH), heptachlor epoxide, dieldrin and polychlorinated biphenyls (PCBs) were determined in human milk of 40 Zimbabwean mothers living in the greater Harare area. Three municipal clinics and one main hospital were randomly selected as collecting points. The main organochlorine contaminants found in all the samples analysed were p,p -DDT and p,p -DDE and the mean levels of sum DDT and DDT/DDE ratio were 6 mg/kg milk fat and 0.74 respectively. In general, relatively low residue levels of alpha-beta-,gamma-HCH, heptachlorepoxide and dieldrin were detected in 58,100,63,13 and 65pc, respectively of all the milk samples analysed. Trace of the PCB congener 2,2,4,5,5'-pentachlorobiphenyl (PCB 101) were found in 15 samples and only one sample contained traces of 2,3',4,4',5-pentachlorobiphenyl (PCB 118). The results were examined with regard to health ad living condition of the mothers. From the small population observed around the greater Harare area--social status, educational background an living conditions could be described as important demographic variables influencing the frequency distribution of residual levels of sum DDT in the mother's milk.
测定了居住在哈拉雷大都市区的40名津巴布韦母亲的母乳中氯代烃p,p -滴滴涕、p,p, -滴滴伊、p,p -滴滴滴、p,p -滴滴涕、α-、β-、γ-六氯环己烷(HCH)、环氧七氯、狄氏剂和多氯联苯(PCBs)的残留水平。随机选择了三家市立诊所和一家主要医院作为采集点。在所有分析样本中发现的主要有机氯污染物是p,p -滴滴涕和p,p -滴滴伊,滴滴涕总量的平均水平和滴滴涕/滴滴伊比率分别为6毫克/千克乳脂和0.74。总体而言,在所有分析的母乳样本中,分别有58%、100%、63%、13%和65%检测到相对较低水平的α-、β-、γ-六氯环己烷、环氧七氯和狄氏剂残留。在15个样本中发现了痕量的多氯联苯同系物2,2,4,5,5'-五氯联苯(PCB 101),只有一个样本含有痕量的2,3',4,4',5-五氯联苯(PCB 118)。针对母亲的健康和生活状况对结果进行了检查。从在哈拉雷大都市区周围观察的小群体来看,社会地位、教育背景和生活条件可被描述为影响母乳中滴滴涕总量残留水平频率分布的重要人口统计学变量。