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[幽门螺杆菌在选择性近端迷走神经切断术后十二指肠溃疡复发病因中的作用]

[Role of Helicobacter pylori in the etiology of duodenal ulcer recurrence after selective proximal vagotomy].

作者信息

Mitrokhina T V, Fitilev S B, Grafskaia N D, Pavlova M V

出版信息

Khirurgiia (Mosk). 1996(2):39-42.

PMID:8754897
Abstract

126 patients with duodenal peptic ulcer were examined before and in different periods after operation for selective proximal vagotomy (SPV). Endoscopy was performed and Helicobacter pylori (HP) was detected by the urease, bacteriological, and histological methods. The urease test proved to be the most informative, simple, and available method for revealing infection of the gastric mucosa by HP. The frequency of HP detection by this method made up 97-98%. The frequency of ulcer recurrences after SPV coincided with the degree of contamination of the mucosa with HP and increased to 15% in high contamination. Treatment with agent eliminating HP in the early period after SPV promoted cicatrization of the ulcer.

摘要

对126例十二指肠消化性溃疡患者在选择性近端迷走神经切断术(SPV)手术前及术后不同时期进行了检查。进行了内镜检查,并通过尿素酶、细菌学和组织学方法检测幽门螺杆菌(HP)。尿素酶试验被证明是揭示胃黏膜HP感染最具信息性、最简单且可行的方法。用这种方法检测HP的频率为97 - 98%。SPV术后溃疡复发的频率与黏膜受HP污染的程度一致,在高污染情况下增至15%。SPV术后早期用消除HP的药物治疗促进了溃疡的愈合。

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