Bulava G V, Nikulina V P
Khirurgiia (Mosk). 1996(2):104-7.
The influence of immunoactive medicines on the cell immunity have been studied. There were differences in reaction to T-activin and Thymalin between various patients with septic postoperative complications. Thymalin stimulated T-cells while acting with immunoglobulins or immune plasmas only. T-activin led to the increase in the number of T-lymphocytes and B-lymphocytes independently of it's cooperation with the vaccines. The stimulating effect of myelopid demonstrated itself by increase in the number of B-lymphocytes and immunoglobulins M and G after 14 days of treatment. The positive clinical effect was more impressive when immunomodulators were used in combinations with the vaccines; still it did not correlate completely with the dynamics of the cell immunity parameters.
已经研究了免疫活性药物对细胞免疫的影响。不同的术后败血症并发症患者对T-激活素和胸腺素的反应存在差异。胸腺素仅在与免疫球蛋白或免疫血浆一起作用时刺激T细胞。T-激活素导致T淋巴细胞和B淋巴细胞数量增加，与其与疫苗的协同作用无关。髓磷质的刺激作用在治疗14天后表现为B淋巴细胞数量以及免疫球蛋白M和G增加。当免疫调节剂与疫苗联合使用时，积极的临床效果更显著；但它与细胞免疫参数的动态变化并不完全相关。
