[支气管肺泡灌洗对慢性过敏性肺泡炎患者预后评估及治疗监测的实用性评价]
[Evaluation of the usefulness of bronchoalveolar lavage for prognosing and monitoring the treatment of patients with chronic allergic alveolitis].
作者信息
Jastrzebski D, Oklek K, Ziora D
机构信息
Katedry i Kliniki Ftizjopneumonologii Slaskiej Akademii Medycznej w Zabrzu.
出版信息
Pneumonol Alergol Pol. 1996;64(3-4):157-64.
In 29 patients with chronic allergic alveolitis broncho-alveolar lavage BAL and lung function tests were performed before and after one year of Prednisone treatment. We observed significantly (p < 0.001) decrease of BAL lymphocytes from 52% to 32% and significantly (p < 0.001) increase of BAL macrophages from 33% to 54%. We found negative correlation between percentage of BAL neutrophils before treatment and annual changes of DLCO (r = 0.37 p < 0.05). Annual changes of lymphocytes negatively correlated with annual changes of DLCO (r = 0.45 p < 0.02) and D/VA (r = 0.46 p < 0.02).
对29例慢性过敏性肺泡炎患者在接受泼尼松治疗一年前后进行了支气管肺泡灌洗（BAL）和肺功能测试。我们观察到BAL淋巴细胞显著减少（p < 0.001），从52%降至32%，同时BAL巨噬细胞显著增加（p < 0.001），从33%增至54%。我们发现治疗前BAL中性粒细胞百分比与DLCO的年度变化之间呈负相关（r = 0.37，p < 0.05）。淋巴细胞的年度变化与DLCO的年度变化呈负相关（r = 0.45，p < 0.02）以及与D/VA呈负相关（r = 0.46，p < 0.02）。
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