Saul'skaia N B, Marsden Ch A
Zh Vyssh Nerv Deiat Im I P Pavlova. 1996 May-Jun;46(3):533-8.
In vivo microdialysis combined with HPLC-EC analysis was used to monitor extracellular dopamine in the medial nucleus accumbens of rats. A conditioned emotional response to a contextual cue was accompanied by a prolonged release of dopamine in the nucleus accumbens. AMPA/kainate antagonist CNQX (100 mcM, intra-accumbens) had no effect on the conditioned dopamine release during the conditioned emotional responses. The data indicate that AMPA/kainate receptors of the nucleus accumbens are not involved in the regulation of the conditioned dopamine release.
采用体内微透析结合高效液相色谱-电化学检测分析法监测大鼠伏隔核内侧的细胞外多巴胺。对情境线索的条件性情绪反应伴随着伏隔核中多巴胺的持续释放。AMPA/海人酸受体拮抗剂CNQX（100微摩尔，伏隔核内注射）对条件性情绪反应期间的条件性多巴胺释放没有影响。数据表明，伏隔核的AMPA/海人酸受体不参与条件性多巴胺释放的调节。
