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[伏隔核谷氨酰胺能输入在联想学习过程中对多巴胺突触释放的调节作用]

[The participation of the glutaminergic input of the nucleus accumbens in regulating the synaptic release of dopamine during associative learning].

作者信息

Saul'skaia N B, Marsden C A

出版信息

Fiziol Zh Im I M Sechenova. 1994 Dec;80(12):45-54.

PMID:7550432
Abstract

The effect of MK-801 on basal and conditioned dopamine release in the rat n. accumbens, was studied. Exposure of the rats to the box where they had been given electrical shock, caused an immediate long lasting increase in the dopamine release. Administration of the MK-801 into the n. accumbens abolished the delayed increase in the dopamine release while exerting no effect on the immediate increase.

摘要

研究了MK-801对大鼠伏隔核中基础和条件性多巴胺释放的影响。将大鼠置于曾遭受电击的盒子中，会导致多巴胺释放立即出现持久增加。向伏隔核注射MK-801消除了多巴胺释放的延迟增加，而对立即增加没有影响。

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