Fernández-Teijeiro A, Piñán M A, Cardenal I, Astigarraga I, Navajas A
Unidad de Oncología Pediátrica, Hospital de Cruces-Baracado, Vizcaya.
Sangre (Barc). 1996 Jun;41(3):245-8.
A child with AIDS is presented who developed L1-ALL while being treated for L3-AL. After achievement of complete remission of the former, he suffered a relapse with L3 morphology. Although the possibilities of a shift in both the morphology and the immunophenotype of ALL in relapse are well known, the rarity of L1-ALL in association with AIDS is stressed by the authors, along with the factors related with the morphologic and phenotypic changes shown by these patients.
报告了一名患有艾滋病的儿童，该儿童在接受L3-AL治疗时发生了L1-ALL。在前者实现完全缓解后，他又出现了L3形态的复发。尽管已知ALL复发时形态和免疫表型会发生转变，但作者强调了L1-ALL与艾滋病相关的罕见性，以及与这些患者所表现出的形态学和表型变化相关的因素。
