Wanic-Kossowska M, Koczocik-Przedpelska J
Kliniki Nefrologii Instytutu Chorób Wewnetrznych Akademii Medycznej im. K. Marcinkowskiego w Poznaniu.
Pol Arch Med Wewn. 1996 Mar;95(3):229-36.
The aim of the study was the analysis of the sequence of electrophysiological changes occurring in the skeletal muscles in patients with chronic renal failure treated with hemodialysis (HD) and intermittent peritoneal dialysis (IPD). In 30 patients (10 treated with IPD-group I, 20 with HD-group II) the global electromyography (EMG) was determined in the muscles: pectoralis, obliqus and rectus abd., biceps brachii, thenar and hypothenar. The fatigue test was determined in the m. biceps brachii. The examinations were done twice during the 12 months of observations. The analysis of the material showed that myoelectrical activity of the examined muscles was significantly lower compared to a control group and did not changed during the 12 months of observations. The results of the fatigue test showed that in uremic patients the fatiguability of m. biceps brachii was significantly greater and was deeper after 12 months of observations. The analysis of the maximal inspiratory and expiratory pressure showed that respiratory muscles in uremic patients were weak. The results of the measurements the hand grip pressure showed that hand muscles were weak also.
本研究旨在分析接受血液透析（HD）和间歇性腹膜透析（IPD）治疗的慢性肾衰竭患者骨骼肌中发生的电生理变化序列。对30例患者（10例接受IPD治疗——I组，20例接受HD治疗——II组）的胸肌、腹斜肌、腹直肌、肱二头肌、鱼际肌和小鱼际肌进行了整体肌电图（EMG）测定。在肱二头肌进行了疲劳试验。在12个月的观察期间进行了两次检查。材料分析表明，与对照组相比，所检查肌肉的肌电活动显著降低，并且在12个月的观察期间没有变化。疲劳试验结果表明，尿毒症患者肱二头肌的疲劳性显著更高，且在观察12个月后更深。最大吸气和呼气压力分析表明，尿毒症患者的呼吸肌较弱。手握力测量结果表明，手部肌肉也较弱。
