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无症状原发性甲状旁腺功能亢进症。

Asymptomatic primary hyperparathyroidism.

作者信息

Birkenhäger J C, Bouillon R

机构信息

Academisch Ziekenhuis, Inwendige Geneeskunde III, Erasmus University, Rotterdam, Netherlands.

出版信息

Postgrad Med J. 1996 Jun;72(848):323-6. doi: 10.1136/pgmj.72.848.323.

Abstract

The prevalence of hypercalcaemia in the adult population is probably between 0.6 and 1.1%, sufferers being predominantly women over 50 years of age. Most apparently asymptomatic hypercalcaemic patients are found to have primary hyperparathyroidism, and may in fact show some symptoms of the condition (lowered bone mineral density, cardiovascular disease and/or neuropsychiatric symptoms). The criteria for surgical intervention in these cases are discussed in the light of the high success rate of parathyroidectomy in experienced hands and the lack of effective alternative treatments.

摘要

成年人群中高钙血症的患病率可能在0.6%至1.1%之间,患者主要为50岁以上的女性。大多数明显无症状的高钙血症患者被发现患有原发性甲状旁腺功能亢进,实际上可能会出现该病症的一些症状(骨矿物质密度降低、心血管疾病和/或神经精神症状)。鉴于经验丰富的医生进行甲状旁腺切除手术的成功率很高,且缺乏有效的替代治疗方法,本文讨论了这些病例的手术干预标准。

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本文引用的文献

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Primary hyperparathyroidism. Low surgical morbidity supports liberal attitude to operation.
Arch Surg. 1994 Mar;129(3):237-40. doi: 10.1001/archsurg.1994.01420270011002.
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Am J Med. 1994 Feb;96(2):101-6. doi: 10.1016/0002-9343(94)90128-7.
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Should primary hyperparathyroidism be treated surgically in elderly patients older than 75 years?
Surgery. 1995 Apr;117(4):397-401. doi: 10.1016/s0039-6060(05)80059-5.

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