[妊娠期艾迪生病：6例报告]
[Addison's disease in pregnancy: a report of six cases].
作者信息
Xia Y, Pan M, Zhang Z
机构信息
Obstetrics and Gynecology Hospital, Shanghai Medical University.
出版信息
Zhonghua Fu Chan Ke Za Zhi. 1996 Apr;31(4):226-8.
OBJECTIVE
To review six cases of pregnancy with Addison's disease at Obstetrics and Gynecology Hospital, Shanghai Medical University from 1949 to 1994.
METHOD
This is a clinical retrospective analysis. Five of the 6 patients were treated with hormone replacement therapy, and the remaining one received no hormone treatment due to lack of symptoms during pregnancy and neglect of previous adrenal surgery by obstetricians.
RESULTS
The patient received no treatment occurred Addisonian crisis and died soon after delivery. The other five patients had smooth course of delivery and postpartum period.
CONCLUSIONS
Hormone replacement therapy is important for patients with Addison's disease in pregnancy especially for acute decompensation of adrenal function. Pregnant women with history of adrenal surgery should be monitored carefully even without any symptoms and hormone treatment is necessary. Vaginal delivery is encouraged unless there is obstetric indication.
目的
回顾1949年至1994年上海医科大学妇产科医院收治的6例妊娠合并艾迪生病的病例。
方法
这是一项临床回顾性分析。6例患者中有5例接受了激素替代治疗，其余1例因孕期无症状且产科医生忽视了既往肾上腺手术史而未接受激素治疗。
结果
未接受治疗的患者发生了肾上腺危象，产后不久死亡。其他5例患者分娩及产褥期过程顺利。
结论
激素替代治疗对妊娠合并艾迪生病的患者很重要，尤其是对于肾上腺功能急性失代偿的患者。有肾上腺手术史的孕妇即使没有任何症状也应仔细监测，且有必要进行激素治疗。除非有产科指征，鼓励经阴道分娩。
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