伯纳特立克次氏体的一个发育阶段特异性组蛋白H1同源物。
A developmental stage-specific histone H1 homolog of Coxiella burnetii.
作者信息
Heinzen R A, Hackstadt T
机构信息
Host-Parasite Interactions Section, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana 59840, USA.
出版信息
J Bacteriol. 1996 Aug;178(16):5049-52. doi: 10.1128/jb.178.16.5049-5052.1996.
Abstract
Two DNA-binding proteins have been detected in Coxiella burnetii by southwestern (DNA-protein) blotting. One of these, termed Hq1, is enriched in the small cell variant stage of the developmental cycle and displays compositional and primary amino acid sequence similarities to eukaryotic histone H1. C. burnetii appears to be another example of an intracellular parasite with morphologically distinct developmental forms whose nucleoid structure may be controlled by histone H1 homologs.
摘要
通过西南（DNA-蛋白质）印迹法在伯氏考克斯氏体中检测到了两种DNA结合蛋白。其中一种被称为Hq1，在发育周期的小细胞变体阶段富集，并且在组成和一级氨基酸序列上与真核组蛋白H1相似。伯氏考克斯氏体似乎是另一个具有形态学上不同发育形式的细胞内寄生虫的例子，其类核结构可能受组蛋白H1同源物的控制。
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