Abel S, Ballas N, Wong L M, Theologis A
Plant Gene Expression Center, Albany, CA 94710, USA.
Bioessays. 1996 Aug;18(8):647-54. doi: 10.1002/bies.950180808.
Genes induced by the plant hormone auxin are probably involved in the execution of vital cellular functions and developmental processes. Experimental approaches designed to elucidate the molecular mechanisms of auxin action have focused on auxin perception, genetic dissection of the signaling apparatus and specific gene activation. Auxin-responsive promoter elements of early genes provide molecular tools for probing auxin signaling in reverse. Functional analysis of several auxin-specific promoters of unrelated early genes suggests combinatorial utilization of both conserved and variable elements. These elements are arranged into autonomous domains and the combination of such modules generates uniquely composed promoters. Modular promoters allow for auxin-mediated transcriptional responses to be revealed in a tissue- and development-specific manner.
由植物激素生长素诱导的基因可能参与重要细胞功能的执行和发育过程。旨在阐明生长素作用分子机制的实验方法主要集中在生长素感知、信号传导装置的遗传剖析以及特定基因的激活上。早期基因的生长素响应启动子元件为反向探究生长素信号传导提供了分子工具。对几个不相关早期基因的生长素特异性启动子的功能分析表明，保守元件和可变元件会组合使用。这些元件被排列成自主结构域，此类模块的组合产生了独特组成的启动子。模块化启动子能够以组织和发育特异性的方式揭示生长素介导的转录反应。
