[Cocaine abuse and mental disease].

The comorbidity between psychiatric diseases and cocaine abuse is extensive. Several studies show that the prevalence of specific personality disorders, eating disorders, attention-deficit-disorder and affective disorders is high in cocaine abusers. Excessive cocaine consumption can lead to a toxic schizophrenic psychosis. The comorbidity has been understood in several ways, using many theoretical approaches. The different hypotheses should not be considered contradictive. Explanations involving genetic, psychosocial, psychological and biological approaches are necessary for a complete understanding of the comorbidity.