Arnaud J P, Casa C, Jacob J P, Ronceray J, Becouarn G, Bergamaschi R
CHU Angers, Service de Chirurgie Viscérale.
J Chir (Paris). 1996 Jun;133(4):155-8.
The records of 143 patients with gallbladder carcinoma operatively treated between 1975 and 1995 were retrospectively reviewed. Abdominal pain was the most common symptom and was present in 103 patients (72%). Jaundice was present in 83 patients (58%) and weight loss in 68 (47.5%). Pre-operative diagnosis was made in 40.5% of the patients. Surgical procedures included cholecystectomy alone (16.8%), cholecystectomy with resection of the hepatic bed and lymphadenectomy (11%), cholecystectomy with biliary drainage (57.3%), and exploration with biopsy (14%). Surgery was considered as curative in 21.5% of the patients. Overall five-year survival rate was 11%. Actuarial 5-year survival rate was 100%, 29% and 23% in patients with T1, T2 and T3 tumors. The five-year survival rate was nil in patients with T4 and T5 cancers.
回顾性分析了1975年至1995年间接受手术治疗的143例胆囊癌患者的病历。腹痛是最常见的症状,103例患者(72%)出现腹痛。83例患者(58%)出现黄疸,68例患者(47.5%)出现体重减轻。40.5%的患者术前得到诊断。手术方式包括单纯胆囊切除术(16.8%)、胆囊切除加肝床切除及淋巴结清扫术(11%)、胆囊切除加胆道引流术(57.3%)以及探查活检术(14%)。21.5%的患者手术被认为是根治性的。总体五年生存率为11%。T1、T2和T3期肿瘤患者的精算5年生存率分别为100%、29%和23%。T4和T5期癌症患者的五年生存率为零。