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Combination chemotherapy with cis-diammine-dichloro-platinum, vinblastine, and bleomycin in advanced testicular non-seminoma.

作者信息

Stoter G, Sleijfer D T, Vendrik C P, Schraffordt Koops H, Struyvenberg A, Van Oosterom A T, Brouwers T M, Pinedo H M

出版信息

Lancet. 1979 May 5;1(8123):941-5. doi: 10.1016/s0140-6736(79)91719-7.

Abstract

40 patients with disseminated testicular non-seminoma were treated with cis-diammine-dichloro-platinum, vinblastine, and bleomycin. Complete remission was achieved in 24 (60%) patients and partial remission in 11 (28%). 22 of the 24 complete responders, who have been followed-up for a median of 11 months, have been tumour-free for 5--30 months. There were 3 drug-related deaths. This regimen is the most effective remission-induction treatment available for disseminated testicular non-seminoma. Patients should be treated in centres experienced in the specialised management of this potentia-ly curable disease.

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