Larvol L, Monier A, Besnier P, Levecq H
Service de Médècine Interne et Gastroentérologie, Hôpital Fontenoy, Chartres.
Gastroenterol Clin Biol. 1996 Mar;20(2):193-5.
Lactobacillus acidophilus is usually considered to be non pathogenic. We report a case of liver abscess due to Lactobacillus acidophilus in a 39 year-old man with chronic pancreatitis complicated by both endocrine and exocrine insufficiency, and with a choledoco-duodenostomy. Lactobacillus acidophilus was isolated in blood and liver samples. Complete recovery of the liver abscess occurred after antibiotherapy. We suggest that the abnormally low duodenal pH secondary to pancreatic insufficiency may have promoted both Lactobacillus acidophilus adhesion and multiplication in this patient. The choledoco-duodenostomy may then have promoted biliary tract colonisation.
嗜酸乳杆菌通常被认为是无致病性的。我们报告了一例39岁男性因嗜酸乳杆菌导致肝脓肿的病例，该患者患有慢性胰腺炎，合并内分泌和外分泌功能不全，并接受了胆总管十二指肠吻合术。在血液和肝脏样本中分离出了嗜酸乳杆菌。抗生素治疗后肝脓肿完全康复。我们认为，继发于胰腺功能不全的十二指肠pH值异常降低可能促进了该患者体内嗜酸乳杆菌的黏附和繁殖。然后，胆总管十二指肠吻合术可能促进了胆道的定植。
