• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

不太友好的细菌。

: the not so friendly bacteria.

作者信息

Pararajasingam Abirami, Uwagwu Juliet

机构信息

Department of General Surgery, Lewisham and Greenwich NHS Trust, London, UK.

Department of Microbiology, Lewisham and Greenwich NHS Trust, London, UK.

出版信息

BMJ Case Rep. 2017 Sep 13;2017:bcr-2016-218423. doi: 10.1136/bcr-2016-218423.

DOI:10.1136/bcr-2016-218423
PMID:28903972
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5612357/
Abstract

We present a 65-year-old diabetic patient with a complex liver abscess and bacteraemia from The abscess resulted in a prolonged hospital stay due to ongoing sepsis despite ultrasound-guided drainage and broad-spectrum antibiotics. Furthermore, the patient developed several secondary complications including a right-sided pleural effusion, an inferior vena cava thrombus and septic lung emboli. The abscess was eventually managed successfully with a prolonged course of antibiotics and multiple ultrasound-guided drainage procedures.To our knowledge, this is the first reported case of probiotic consumption, confirmed by strain identification, as the likely source of a liver abscess. Probiotic products have been widely used for many years and are advocated to the general public for their health benefits with no warning of side effects. Lactobacilli are one group of bacteria commonly used in these products. Although rare, complications have been reported. Susceptible patients, such as those who are immunocompromised, should be advised against excessive consumption.

摘要

我们报告了一名65岁的糖尿病患者,患有复杂的肝脓肿并伴有菌血症。尽管进行了超声引导下引流和使用了广谱抗生素,但由于持续的脓毒症,脓肿导致患者住院时间延长。此外,患者还出现了几种继发性并发症,包括右侧胸腔积液、下腔静脉血栓和脓毒性肺栓塞。最终,通过延长抗生素疗程和多次超声引导下引流手术,脓肿得到了成功治疗。据我们所知,这是首例经菌株鉴定证实益生菌摄入可能是肝脓肿来源的报告病例。益生菌产品已广泛使用多年,并因其对健康有益而向公众推广,且未警告有副作用。乳酸杆菌是这些产品中常用的一类细菌。虽然并发症很少见,但已有报道。对于易感患者,如免疫功能低下者,应建议避免过量食用。

相似文献

1
: the not so friendly bacteria.不太友好的细菌。
BMJ Case Rep. 2017 Sep 13;2017:bcr-2016-218423. doi: 10.1136/bcr-2016-218423.
2
Probiotic lactobacilli and bacteraemia in Stockholm.斯德哥尔摩的益生菌乳酸杆菌与菌血症
Scand J Infect Dis. 2006;38(5):327-31. doi: 10.1080/00365540500449826.
3
Lactobacillus sepsis associated with probiotic therapy.与益生菌治疗相关的乳酸杆菌败血症
Pediatrics. 2005 Jan;115(1):178-81. doi: 10.1542/peds.2004-2137.
4
Liver abscess and bacteremia caused by lactobacillus: role of probiotics? Case report and review of the literature.乳酸杆菌引起的肝脓肿和菌血症:益生菌的作用?病例报告及文献综述
BMC Gastroenterol. 2016 Nov 18;16(1):138. doi: 10.1186/s12876-016-0552-y.
5
Liver abscess due to a Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG.由一株与鼠李糖乳杆菌GG株无法区分的鼠李糖乳杆菌引起的肝脓肿。
Clin Infect Dis. 1999 May;28(5):1159-60. doi: 10.1086/514766.
6
Safety of Lactobacillus strains used as probiotic agents.用作益生菌制剂的乳酸杆菌菌株的安全性。
Clin Infect Dis. 2002 May 1;34(9):1283-4; author reply 1284-5. doi: 10.1086/339947.
7
The potential risks of probiotics among HIV-infected persons: Bacteraemia due to Lactobacillus acidophilus and review of the literature.艾滋病毒感染者中益生菌的潜在风险:嗜酸乳杆菌引起的菌血症及文献综述
Int J STD AIDS. 2016 Nov;27(13):1223-1230. doi: 10.1177/0956462415590725. Epub 2015 Jun 30.
8
Bacteraemia and liver abscess due to .由……引起的菌血症和肝脓肿。 (你提供的原文不完整,缺少具体病因)
BMJ Case Rep. 2017 Jul 27;2017:bcr-2017-220654. doi: 10.1136/bcr-2017-220654.
9
Safety of probiotics that contain lactobacilli or bifidobacteria.含有乳酸菌或双歧杆菌的益生菌的安全性。
Clin Infect Dis. 2003 Mar 15;36(6):775-80. doi: 10.1086/368080. Epub 2003 Mar 5.
10
Portal vein thrombosis and liver abscess due to Lactococcus lactis.乳酸乳球菌导致的门静脉血栓形成和肝脓肿
Turk J Gastroenterol. 2006 Jun;17(2):144-7.

引用本文的文献

1
Lactobacillus paracasei-induced lung abscess in a splenectomized patient: A rare case report.脾切除患者中副干酪乳杆菌引起的肺脓肿:一例罕见病例报告。
Medicine (Baltimore). 2025 Jul 11;104(28):e43162. doi: 10.1097/MD.0000000000043162.
2
Exploring the Potential of Novel Animal-Origin Probiotics as Key Players in One Health: Opportunities and Challenges.探索新型动物源益生菌作为“同一健康”关键参与者的潜力:机遇与挑战。
Int J Mol Sci. 2025 May 27;26(11):5143. doi: 10.3390/ijms26115143.
3
The Safety of Probiotics Intended for Use in Pregnant and Lactating Women: From a Desirable to a Required Task.用于孕妇和哺乳期妇女的益生菌安全性:从一项理想任务变为一项必要任务。
Foods. 2024 Dec 12;13(24):4024. doi: 10.3390/foods13244024.
4
Bacteriocins: potentials and prospects in health and agrifood systems.细菌素:健康与农业食品系统中的潜力与前景
Arch Microbiol. 2024 Apr 25;206(5):233. doi: 10.1007/s00203-024-03948-y.
5
Accounting for the health risk of probiotics.考虑益生菌的健康风险。
Heliyon. 2024 Mar 10;10(6):e27908. doi: 10.1016/j.heliyon.2024.e27908. eCollection 2024 Mar 30.
6
Therapeutic Evaluation of subsp. MH-02 as an Adjunctive Treatment in Patients with Reflux Esophagitis: A Randomized, Double-Blind, Placebo-Controlled Trial.亚抑菌浓度 MH-02 辅助治疗反流性食管炎的疗效评价:一项随机、双盲、安慰剂对照试验。
Nutrients. 2024 Jan 24;16(3):342. doi: 10.3390/nu16030342.
7
Proton pump inhibitor-induced gut dysbiosis and immunomodulation: current knowledge and potential restoration by probiotics.质子泵抑制剂诱导的肠道菌群失调和免疫调节:益生菌的现有知识和潜在恢复作用。
Pharmacol Rep. 2023 Aug;75(4):791-804. doi: 10.1007/s43440-023-00489-x. Epub 2023 May 4.
8
Dietary administration with hydrolyzed silk sericin improves the intestinal health of diabetic rats.食用水解丝胶蛋白可改善糖尿病大鼠的肠道健康。
Front Microbiol. 2023 Mar 7;14:1074892. doi: 10.3389/fmicb.2023.1074892. eCollection 2023.
9
Promotes Recovery of the Colon Barrier in Septic Mice through Accelerating ISCs Regeneration.通过加速 ISCs 再生促进脓毒症小鼠结肠屏障的恢复。
Nutrients. 2023 Jan 28;15(3):672. doi: 10.3390/nu15030672.
10
Comprehensive analysis of 84 strains uncovers their genetic diversity, functional characteristics, and potential risks.综合分析 84 株菌,揭示其遗传多样性、功能特性和潜在风险。
Front Cell Infect Microbiol. 2023 Jan 4;12:919701. doi: 10.3389/fcimb.2022.919701. eCollection 2022.

本文引用的文献

1
Liver abscess and bacteremia caused by lactobacillus: role of probiotics? Case report and review of the literature.乳酸杆菌引起的肝脓肿和菌血症:益生菌的作用?病例报告及文献综述
BMC Gastroenterol. 2016 Nov 18;16(1):138. doi: 10.1186/s12876-016-0552-y.
2
Alterations in fecal microbiota composition by probiotic supplementation in healthy adults: a systematic review of randomized controlled trials.健康成年人补充益生菌对粪便微生物群组成的影响:随机对照试验的系统评价
Genome Med. 2016 May 10;8(1):52. doi: 10.1186/s13073-016-0300-5.
3
Probiotics for preventing urinary tract infections in adults and children.用于预防成人和儿童尿路感染的益生菌。
Cochrane Database Syst Rev. 2015 Dec 23;2015(12):CD008772. doi: 10.1002/14651858.CD008772.pub2.
4
Treatment and prevention of pouchitis after ileal pouch-anal anastomosis for chronic ulcerative colitis.慢性溃疡性结肠炎回肠储袋肛管吻合术后储袋炎的治疗与预防
Cochrane Database Syst Rev. 2015 Nov 23(11):CD001176. doi: 10.1002/14651858.CD001176.pub3.
5
Probiotics for preventing acute upper respiratory tract infections.用于预防急性上呼吸道感染的益生菌。
Cochrane Database Syst Rev. 2015 Feb 3(2):CD006895. doi: 10.1002/14651858.CD006895.pub3.
6
Descending necrotizing mediastinitis associated with Lactobacillus plantarum.与植物乳杆菌相关的下行性坏死性纵隔炎
BMC Infect Dis. 2013 Aug 29;13:398. doi: 10.1186/1471-2334-13-398.
7
Lactobacillus rhamnosus administration causes sepsis in a cardiosurgical patient--is the time right to revise probiotic safety guidelines?罗伊氏乳杆菌给药导致心外科患者发生脓毒症——是否到了修订益生菌安全性指南的时候?
Clin Microbiol Infect. 2011 Oct;17(10):1589-92. doi: 10.1111/j.1469-0691.2011.03614.x. Epub 2011 Aug 16.
8
The impact of diabetes on the pathogenesis of sepsis.糖尿病对脓毒症发病机制的影响。
Eur J Clin Microbiol Infect Dis. 2012 Apr;31(4):379-88. doi: 10.1007/s10096-011-1337-4. Epub 2011 Jul 30.
9
Lactobacillus probiotic use in cardiothoracic transplant recipients: a link to invasive Lactobacillus infection?心脏移植受者中使用益生菌乳酸杆菌:与侵袭性乳酸杆菌感染有关联?
Transpl Infect Dis. 2010 Dec;12(6):561-4. doi: 10.1111/j.1399-3062.2010.00580.x. Epub 2010 Oct 7.
10
[Lactobacillus rhamnosus septicemia in a diabetic patient associated with probiotic use: a case report].[一名糖尿病患者使用益生菌后发生鼠李糖乳杆菌败血症:病例报告]
Ann Biol Clin (Paris). 2008 Mar-Apr;66(2):195-8. doi: 10.1684/abc.2008.0210.