Lesur G, Bergemer A M, Turner L, Parlier H, Bernades P, Dupuy P
Service d'Hépato-Gastroentérologie, Hôpital Ambroise-Paré, Boulogne.
Gastroenterol Clin Biol. 1996 Mar;20(2):204-6.
We report two cases of metastatic non-functioning pancreatic endocrine tumour with very elevated plasma levels of alpha-fetoprotein. In these two cases, serial plasma levels of alpha-fetoprotein, initially normal, correlated well with hepatic tumour progression and were associated with fatal outcome. These results suggest that elevated plasma concentration of alpha-fetoprotein may be caused by metastatic pancreatic endocrine tumour and than alpha-fetoprotein serial measurement may be useful in prognostic evaluation.
我们报告了两例转移性无功能性胰腺内分泌肿瘤患者，其血浆甲胎蛋白水平显著升高。在这两例患者中，甲胎蛋白的系列血浆水平最初正常，与肝肿瘤进展密切相关，并与致命结局相关。这些结果表明，血浆甲胎蛋白浓度升高可能由转移性胰腺内分泌肿瘤引起，并且甲胎蛋白系列检测可能有助于预后评估。
