Grosshans E
Clinique dermatologique des hôpitaux universitaires de Strasbourg, Université Louis-Pasteur.
Rev Prat. 1996 Apr 15;46(8):968-73.
The main cutaneous manifestation of allergy is eczema. In atopic dermatitis, the epidermal Langerhans cells express receptors for IgE and the eczematous lesions may be associated with other atopic disorders such as asthma or pollinosis. In contact dermatitis, the epidermal Langerhans' cells play the role of antigen-presenting cells; the antigens eliciting the eczematous lesions may be of occupational, vestimentary, cosmetical, therapeutical or other environmental origin. Epicutaneous test procedures enable their identification. Paraptic eczema is a concept including all the cutaneous and systemic complications of contact dermatitis.
过敏的主要皮肤表现是湿疹。在特应性皮炎中,表皮朗格汉斯细胞表达IgE受体,湿疹性病变可能与其他特应性疾病如哮喘或花粉症相关。在接触性皮炎中,表皮朗格汉斯细胞起抗原呈递细胞的作用;引发湿疹性病变的抗原可能源于职业、衣物、化妆品、治疗或其他环境因素。表皮试验程序能够识别这些抗原。旁发性湿疹是一个包括接触性皮炎所有皮肤和全身并发症的概念。