Dalger J M, Jezequel R, Buisson P, Le Marec C, Dumas P, Le Guern G, Boutin J P, Thebault L
Service d'Anesthésie-Réanimation, HIA Clermont-Tonnerre, Brest-Naval.
Cah Anesthesiol. 1996;44(1):97-100.
The purpose of this study was to assess the analgesic effects of intra-articular injection of a morphine-bupivacaine combination following knee arthroscopy. 47 patients were evaluated. Knee arthroscopies were all performed under general anaesthesia, using propofol, alfentanil, isoflurane and nitrous oxide. Analgesic effects were evaluated by a visual analogic pain scale. Serum bupivacaine was measured during the first 8 postoperative hours. Analgesia was good in the immediate postoperative period, with minimal side effects. The serum bupivacaine levels were low. However the analgesic efficacy of intra-articular injection of morphine-bupivacaine should be corroborated through a double blind study.
本研究的目的是评估膝关节镜检查后关节腔内注射吗啡-布比卡因合剂的镇痛效果。对47例患者进行了评估。所有膝关节镜检查均在全身麻醉下进行，使用丙泊酚、阿芬太尼、异氟烷和氧化亚氮。通过视觉模拟疼痛量表评估镇痛效果。术后头8小时内测定血清布比卡因含量。术后即刻镇痛效果良好，副作用极小。血清布比卡因水平较低。然而，关节腔内注射吗啡-布比卡因的镇痛效果应通过双盲研究加以证实。
