[Study on the effect and mechanism of qinggan xiehuo decoction in treatment of endotoxin-induced uveitis in rabbits].

The therapeutic efficacy of Qinggan Xiehuo Decoction (QGXHD) on rabbit model of uveitis (1) The symptoms of Liver-Fire such as conjunctival congestion, thirsty dark urine, oliguria, irritability and rapid pulse were markedly relieved (P < 0.05-0.01); (2) The ophthalmic signs, iris hyperemia and aqueous humor turbidity observed through slit-lamp were improved significantly (P < 0.01); (3) The inflammatory infiltration, the protein content and leukocyte count in the aqueous humor decreased markedly (P < 0.01); (4) The concentration of inflammatory mediators in blood and aqueous humor were reduced. (5) Pathological examination showed that the QGXHD could protect the capillary, blood-aqueous barrier and alleviated the uveal damage caused by endotoxin.