[Effect of inhaled corticosteroids on serum eosinophil cationic protein and sIL-2R levels in asthmatics pulmonary hypertension].

To study the influence of corticosteroid and beta 2-agonist on eosinophil and T lymphocyte functioning state in the asthmatics, we measured the serum ECP sIL-2R levels and airway reactivity before and after 6-week treatment with beclometasone and terbutalin. The result revealed that after inhalation of steroid, the serum ECP sIL-2R levels decreased, whereas the lung function improved and MCH-PC20 values increased. It suggested that steroid could inhibit activation of eosinophil and T lymphocyte as well as show the effect of anti-inflammation and reducing AHR.