Li S, Cai H, Guo J
Department of Pediatric Ophthalmology, First School of Clinical Medicine, Beijing Medical University.
Zhonghua Yan Ke Za Zhi. 1995 Nov;31(6):422-5.
We investigated the characteristics of visual evoked potentials (VEPs) of the eyes with normal visual acuity in 84 children of whom 20 were normal, 28 of anisometropic amblyopia, 8 of anisometropic amblyopia already cured, 8 pairs of monozygotic and 6 pairs of dizygotic twins with amblyopia. The results showed that although the fellow eye of an amblyopic eye or the cured amblyopic eye had normal visual acuity, the VEPs presented abnormal, the marked abnormality being the prolongation of the latency of P100 peak. No significant difference was found in VEPs between the eye with normal visual acuity and the eye with amblyopia in the monozygotic twins with the same genetic background (P > 0.05). This study demonstrated that possibly the clinical examinations of visual acuity and VEPs reflect different visual information processes, and the "normal" eyes of amblyopes are not normal.
我们对84名儿童视力正常的眼睛的视觉诱发电位(VEP)特征进行了研究,其中20名儿童视力正常,28名患有屈光参差性弱视,8名屈光参差性弱视已治愈,8对单卵双胞胎和6对双卵双胞胎患有弱视。结果显示,尽管弱视眼的对侧眼或已治愈的弱视眼视力正常,但其VEP表现异常,显著异常为P100波峰潜伏期延长。在具有相同遗传背景的单卵双胞胎中,视力正常的眼睛与弱视眼的VEP之间未发现显著差异(P>0.05)。本研究表明,视力和VEP的临床检查可能反映了不同的视觉信息处理过程,弱视患者的“正常”眼睛并非正常。