[弱视儿童视觉诱发电位曲线参数的变化]
[Changes in visual evoked potentials curve parameters in children with amblyopia].
作者信息
Karlica Dobrila, Galetović Davor, Bućan Kajo, Znaor Ljubo, Skelin Sinisa
机构信息
University Department of Ophthalmology, Split University Hospital Center, Split, Croatia.
出版信息
Acta Med Croatica. 2009 Oct;63(4):321-4.
AIM
The aim of the study was to correlate visual evoked potential (VEP) parameters (amplitude and latency) with visual acuity of the amblyopic eye.
PATIENTS AND METHODS
The study included 30 children aged 4.5-6 years, tested for visual acuity before refractive correction, with correction, and after pleoptic therapy. In addition, VEP parameters were recorded according to changes in visual acuity.
RESULTS
VEP curves were found to change with visual acuity of the amblyopic eye. A statistically significant correlation was obtained between amplitude values and visual acuity as well as between latency values and visual acuity (P<0.001 both).
DISCUSSION
Some authors have reported differences in VEP curve parameters according to visual acuity. We performed VEP assessment in children with anisometropic amblyopia and found statistically significant differences among the values obtained before refractive correction, with refractive correction and after pleoptic treatment of amblyopic eye. VEP curve values changed with improvement in visual acuity: the P100 wave amplitude was higher and latency shorter.
CONCLUSION
VEP may be a valid method to determine amblyopia.
目的
本研究的目的是将视觉诱发电位（VEP）参数（振幅和潜伏期）与弱视眼的视力相关联。
患者与方法
该研究纳入了30名4.5至6岁的儿童，在屈光矫正前、矫正时以及进行弱视训练治疗后检测其视力。此外，根据视力变化记录VEP参数。
结果
发现VEP曲线随弱视眼的视力而变化。在振幅值与视力之间以及潜伏期值与视力之间均获得了具有统计学意义的相关性（两者P均<0.001）。
讨论
一些作者报告了根据视力不同VEP曲线参数存在差异。我们对屈光参差性弱视儿童进行了VEP评估，发现在屈光矫正前、屈光矫正时以及弱视眼进行弱视训练治疗后所获得的值之间存在统计学意义的差异。VEP曲线值随视力的改善而变化：P100波振幅更高且潜伏期更短。
结论
VEP可能是一种确定弱视的有效方法。
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