Douche C, Benabdesselam A, Mokhtari F, Le Mer Y
Service d'Ophtalmologie, Centre Hospitalier, Montreuil.
J Fr Ophtalmol. 1996;19(5):330-4.
To verify incidence of toxoplasmosis seroconversion during pregnancy and the interest of treating the mother.
Among 7044 infants born between January 1989 and December 1993, 78 (1.1%) born to mothers who developped toxoplasmosis seroconversion during pregnancy were followed.
Among 69 mothers treated, there were only 9 cases of congenital toxoplasmosis (13.4%) including only 3 cases of patent toxoplasmosis.
Treating the mother is an effective means of preventing toxoplasmosis. The cost of verifying seronegativity in women during pregnancy could be reduced by primary prevention.
验证孕期弓形虫血清学转换的发生率以及治疗母亲的意义。
在1989年1月至1993年12月出生的7044名婴儿中,对78名(1.1%)母亲在孕期发生弓形虫血清学转换的婴儿进行了随访。
在69名接受治疗的母亲中,仅有9例先天性弓形虫病(13.4%),其中仅3例为活动性弓形虫病。
治疗母亲是预防弓形虫病的有效手段。通过一级预防可降低孕期女性血清学阴性检测的成本。