Pearson C R, Thomas M R, Cox H J, Garth R J
Department of Otolaryngology, Royal Naval Hospital, Hants, UK.
J Laryngol Otol. 1996 Jun;110(6):527-30. doi: 10.1017/s0022215100134176.
A prospective randomized controlled study was carried out to investigate the effect of prophylactic antibiotic ear drops used for five days after bilateral grommet insertion. The average improvement in the hearing threshold was significantly better in ears in which there was an effusion (16 dB) compared with no effusion (9 dB). The drops had no significant effect upon grommet function at three months measured by blockage rates, extrusion rates or improvement in pure tone audiometry whether or not there was an effusion. The drops were not therefore cost-effective.
进行了一项前瞻性随机对照研究，以调查双侧鼓膜置管术后使用预防性抗生素耳滴5天的效果。与无积液的耳朵（9分贝）相比，有积液的耳朵听力阈值的平均改善情况明显更好（16分贝）。通过堵塞率、脱出率或纯音听力测定的改善情况来衡量，无论有无积液，这些耳滴在三个月时对鼓膜功能均无显著影响。因此，这些耳滴不具有成本效益。
