Chopra S, Levell N J, Cowley G, Gilkes J J
Department of Dermatology, University College London Hospitals, U.K.
Br J Dermatol. 1996 Jun;134(6):1109-12.
A patient is described with the characteristic features of phenytoin hypersensitivity syndrome (PHS) including fever, erythroderma, tibial and facial oedema, pinhead-sized facial pustules and abnormal liver function tests. The use of systemic corticosteroids in this condition is not established. We report the resolution of all the features of PHS with systemic corticosteroids and recurrence on withdrawal, and further remission on reinstitution of systemic corticosteroids.
描述了一名患有苯妥英钠超敏反应综合征（PHS）特征性表现的患者，包括发热、红皮病、胫骨和面部水肿、针头大小的面部脓疱以及肝功能检查异常。全身性皮质类固醇在这种情况下的应用尚无定论。我们报告了全身性皮质类固醇治疗后PHS的所有特征均得到缓解，停药后复发，再次使用全身性皮质类固醇后进一步缓解。
