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[胰腺囊性肿瘤。囊腺瘤和囊腺癌。诊断与管理]

[Cystic tumors of the pancreas. Cystadenomas and cystadenocarcinomas. Diagnosis and management].

作者信息

Wakim R, Houry S, Huguier M

机构信息

Service de Chirurgie Digestive (Pr Huguier), Hôpital Tenon, Paris.

出版信息

J Chir (Paris). 1996 Apr;133(2):54-60.

PMID:8763561
Abstract

Thirteen cases of cystic tumours of the pancreas were studied: serous cystadenomas (CS) = 4, mucinous cystadenomas (MC) = 4 and cystadenocarcinomas (CC) = 5. There were 9 females and 4 males, mean age 60 years (range 44 to 89 years). Two patients had no clinical manifestations, six (2 MC and 4 CC) had a weight loss (3-10 kg). One patient with CC had jaundice. Tumours of the pancreas were diagnosed with sonographic or CT-scan examinations. Eight were localized in the head of the pancreas, two in the body and three in the tail. The cystic tumour remained unknown after preoperative explorations in three cases. The exact nature of the tumour was identified preoperatively in four cases (SC, MC and two CC). Final diagnosis was obtained after histological examination of the surgical specimen in nine cases, by surgical puncture in one case and due to the presence of liver metastases in one case and ultrasound guided needle biopsy in one other. One patient refused all surgery. Ten patients were operated: four had duodenopancreatectomy (SC and three CC), three had tumour exeresis (SC and two MC), two had caudal splenopancreatectomy (MC and CC) and one had surgical puncture (SC). Clinical surveillance is justified in cases with asymptomatic. SC if certain diagnosis has been obtained. Other cystic tumours of the pancreas should be removed, either because there is doubt as to the exact nature of the tumour; because of symptoms induced by SC or because a MC or CC has been identified. In this latter case, the prognosis appears to be better than for non-metastasis exocrine cancer of the pancreas.

摘要

对13例胰腺囊性肿瘤进行了研究:浆液性囊腺瘤(CS)4例,黏液性囊腺瘤(MC)4例,囊腺癌(CC)5例。患者中女性9例,男性4例,平均年龄60岁(范围44至89岁)。2例患者无临床表现,6例(2例MC和4例CC)有体重减轻(3 - 10千克)。1例CC患者出现黄疸。胰腺肿瘤通过超声或CT扫描检查确诊。8例位于胰头,2例位于胰体,3例位于胰尾。3例患者术前探查后仍未明确囊性肿瘤的性质。4例(SC、MC和2例CC)术前确定了肿瘤的确切性质。9例通过手术标本的组织学检查获得最终诊断,1例通过手术穿刺,1例因存在肝转移,另1例通过超声引导下针吸活检。1例患者拒绝所有手术。10例患者接受了手术:4例行十二指肠胰切除术(SC和3例CC),3例行肿瘤切除术(SC和2例MC),2例行胰尾脾切除术(MC和CC),1例行手术穿刺(SC)。对于无症状的病例,若已明确诊断为SC,进行临床监测是合理的。其他胰腺囊性肿瘤应予以切除,原因如下:一是对肿瘤的确切性质存在疑问;二是SC引起了症状;三是已确诊为MC或CC。在后一种情况下,其预后似乎优于胰腺非转移性外分泌癌。

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