Kabiri H, Albouzidi A, Rachid K, Lezrek M, Bousselman N, Benomar S, Draoui D
Service d'Urologie, Hôpital Militaire d'Instruction Mohammed V, Rabat, Maroc.
Prog Urol. 1996 Jun;6(3):439-42.
The Buschke-Loewenstein tumour (BLT) is a sexually transmissible benign tumour of viral origin. It is characterized by a large tumour volume, the possibility of local recurrence and especially its potential for malignant transformation. We report a case of scrotal BLT in a 49-year-old patient with a history of recurrent scrotal fistula, with negative HIV serology, but in whom the search for Human Papilloma Virus (HPV) was not performed. The tumour arising from the scrotal skin was resected and the testis was found to be normal. Histology confirmed transformation of the tumour into a squamous cell carcinoma. The clinical course was favourable, after a follow-up of 8 months with no local recurrence. In the light of this case of rare tumour, especially in its malignant form and its unusual scrotal site, the authors review the problems related to clinical classification, histology (differential diagnosis with primary squamous cell carcinoma), clinical course and treatment raised by this tumour.
Buschke-Loewenstein肿瘤（BLT）是一种起源于病毒的性传播良性肿瘤。其特点是肿瘤体积大、有局部复发的可能，尤其是有恶变的潜能。我们报告一例49岁患有复发性阴囊瘘病史的患者发生阴囊BLT，HIV血清学检查为阴性，但未进行人乳头瘤病毒（HPV）检测。起源于阴囊皮肤的肿瘤被切除，睾丸正常。组织学检查证实肿瘤已转变为鳞状细胞癌。随访8个月无局部复发，临床过程良好。鉴于这例罕见肿瘤病例，尤其是其恶性形式及不寻常的阴囊部位，作者回顾了该肿瘤在临床分类、组织学（与原发性鳞状细胞癌的鉴别诊断）、临床过程及治疗方面的相关问题。
