el Mejjad Amine, Dakir Mohamed, Tahiri Mohamed, Attar Hichame, Cherkaoui Abdeltif, Araki Ahmed, Aboutaieb Rachid, Meziane Fethi
Service d'Urologie B, Centre Hospitalier Universitaire, Ibn Rochd, Casablanca, Maroc.
Prog Urol. 2003 Jun;13(3):513-7.
Buske-Lowenstein tumour (BLT) is a giant condyloma acuminata characterized by a potential for malignant transformation and invasion and recurrence after treatment. It is a rare viral disease, essentially transmitted by sexual intercourse. The objective of this study was to evaluate the epidemiology, clinical features, classification and prognosis of this disease and to outline the treatment modalities. The authors report 3 unusual cases of Buske-Lowenstein tumour involving the scrotum in 2 cases and associated with malignant transformation in 1 case. All three patients (1 woman and two men) presented a history of high-risk sexual behaviour. BLT was confirmed by biopsy and was treated by complete surgical resection. The postoperative course was uneventful without recurrence. Treatment has not been clearly defined and is essentially based on surgery. Sexual education and early treatment of condylomatous lesions can improve the prognosis of this disease. In the light of these cases, the authors emphasize the importance of prevention for all sexually transmissible infections based on sexual education.
Buske-Lowenstein肿瘤（BLT）是一种巨大尖锐湿疣，其特征为具有恶变、侵袭及治疗后复发的可能性。它是一种罕见的病毒性疾病，主要通过性交传播。本研究的目的是评估该疾病的流行病学、临床特征、分类及预后，并概述其治疗方式。作者报告了3例不寻常的Buske-Lowenstein肿瘤病例，其中2例累及阴囊，1例伴有恶变。所有3例患者（1名女性和2名男性）均有高危性行为史。BLT经活检确诊，采用手术完整切除进行治疗。术后过程顺利，无复发。治疗方法尚未明确界定，主要基于手术。性教育及尖锐湿疣病变的早期治疗可改善该疾病的预后。鉴于这些病例，作者强调基于性教育对所有性传播感染进行预防的重要性。
